LTC4S (NM_145867) Human Recombinant Protein
Product Specifications
Background
The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family includes a number of human proteins, several of which are involved the production of leukotrienes. This gene encodes an enzyme that catalyzes the first step in the biosynthesis of cysteinyl leukotrienes, potent biological compounds derived from arachidonic acid. Leukotrienes have been implicated as mediators of anaphylaxis and inflammatory conditions such as human bronchial asthma. This protein localizes to the nuclear envelope and adjacent endoplasmic reticulum. [provided by RefSeq, Jul 2008]
Synonyms
MGC33147
Gene ID
4056
UniProt
Q16873
Accession Number mRNA
NM_145867
Chromosomal Location
5q35.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Arachidonic acid metabolism, Metabolic pathways
Field of Research
Arachidonic acid metabolism, Metabolic pathways
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Activity
27791009
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transmembrane
Molecular Weight
16.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
LTC4S
Species
Human
Protein ID
NP_665874
Overview
Recombinant protein of human leukotriene C4 synthase (LTC4S)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/4056
Uniprot URL
https://www.uniprot.org/uniprot/Q16873
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_145867
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_665874
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