KCTD17 (NM_024681) Human Recombinant Protein
Product Specifications
Background
This gene encodes a protein that belongs to a conserved family of potassium channel tetramerization domain (KCTD) -containing proteins. The encoded protein functions in ciliogenesis by acting as a substrate adaptor for the cullin3-based ubiquitin-conjugating enzyme E3 ligase, and targets trichoplein, a keratin-binding protein, for degradation via polyubiquitinylation. A mutation in this gene is associated with autosomal dominant myoclonic dystonia 26. [provided by RefSeq, Nov 2016]
Overview
Recombinant protein of human potassium channel tetramerisation domain containing 17 (KCTD17)
Synonyms
FLJ12242; FLJ98761
Gene ID
79734
UniProt
Q8N5Z5
Accession Number mRNA
NM_024681
Chromosomal Location
22q12.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Ion Channels: Other
Molecular Weight
33.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
KCTD17
Species
Human
Protein ID
NP_078957
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/79734
Uniprot URL
https://www.uniprot.org/uniprot/Q8N5Z5
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_024681
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_078957
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