POGLUT3 (NM_153705) Human Recombinant Protein

Product Specifications

Background

Protein glucosyltransferase that catalyzes the transfer of glucose from UDP-glucose to a serine residue within the consensus sequence peptide C-X-N-T-X-G-S-F-X-C (PubMed:30127001) . Can also catalyze the transfer of xylose from UDP-xylose but less efficiently (PubMed:30127001) . Specifically targets extracellular EGF repeats of proteins such as NOTCH1 and NOTCH3 (PubMed:30127001) . May regulate the transport of NOTCH1 and NOTCH3 to the plasma membrane and thereby the Notch signaling pathway (PubMed:30127001) .[UniProtKB/Swiss-Prot Function]

Overview

Recombinant protein of human KDEL (Lys-Asp-Glu-Leu) containing 2 (KDELC2)

Synonyms

KDELC2

Gene ID

143888

UniProt

Q7Z4H8, A0A024R3C4

Accession Number mRNA

NM_153705

Chromosomal Location

11q22.3

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

58.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.