POGLUT3 (NM_153705) Human Recombinant Protein
Product Specifications
Background
Protein glucosyltransferase that catalyzes the transfer of glucose from UDP-glucose to a serine residue within the consensus sequence peptide C-X-N-T-X-G-S-F-X-C (PubMed:30127001) . Can also catalyze the transfer of xylose from UDP-xylose but less efficiently (PubMed:30127001) . Specifically targets extracellular EGF repeats of proteins such as NOTCH1 and NOTCH3 (PubMed:30127001) . May regulate the transport of NOTCH1 and NOTCH3 to the plasma membrane and thereby the Notch signaling pathway (PubMed:30127001) .[UniProtKB/Swiss-Prot Function]
Synonyms
KDELC2
Gene ID
143888
UniProt
Q7Z4H8, A0A024R3C4
Accession Number mRNA
NM_153705
Chromosomal Location
11q22.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
58.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
POGLUT3
Species
Human
Protein ID
NP_714916
Overview
Recombinant protein of human KDEL (Lys-Asp-Glu-Leu) containing 2 (KDELC2)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/143888
Uniprot URL
https://www.uniprot.org/uniprot/Q7Z4H8
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_153705
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_714916
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