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TXNDC (TMX1) (NM_030755) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and one transmembrane domain. Unlike most members of this gene family, it lacks a C-terminal ER-retention sequence. The mature membrane-bound protein can both oxidize and reduce disulfide bonds and acts selectively on membrane-associated polypeptides. [provided by RefSeq, Jan 2017]

Overview

Recombinant protein of human thioredoxin-related transmembrane protein 1 (TMX1)

Synonyms

PDIA11; TMX; TXNDC; TXNDC1

Gene ID

81542

UniProt

Q9H3N1

Accession Number mRNA

NM_030755

Chromosomal Location

14q22.1

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Transcription Factors, Transmembrane

Molecular Weight

31.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

TMX1

Species

Human

Protein ID

NP_110382

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/81542

Uniprot URL

https://www.uniprot.org/uniprot/Q9H3N1

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_030755

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_110382

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