TXNDC (TMX1) (NM_030755) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and one transmembrane domain. Unlike most members of this gene family, it lacks a C-terminal ER-retention sequence. The mature membrane-bound protein can both oxidize and reduce disulfide bonds and acts selectively on membrane-associated polypeptides. [provided by RefSeq, Jan 2017]
Overview
Recombinant protein of human thioredoxin-related transmembrane protein 1 (TMX1)
Synonyms
PDIA11; TMX; TXNDC; TXNDC1
Gene ID
81542
UniProt
Q9H3N1
Accession Number mRNA
NM_030755
Chromosomal Location
14q22.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transcription Factors, Transmembrane
Molecular Weight
31.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
TMX1
Species
Human
Protein ID
NP_110382
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/81542
Uniprot URL
https://www.uniprot.org/uniprot/Q9H3N1
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_030755
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_110382
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog