CIPC (NM_033426) Human Recombinant Protein
Product Specifications
Background
Transcriptional repressor which may act as a negative-feedback regulator of CLOCK-ARNTL/BMAL1 transcriptional activity in the circadian-clock mechanism. May stimulate ARNTL/BMAL1-dependent phosphorylation of CLOCK. However, the physiogical relevance of these observations is unsure, since experiments in an animal model showed that CIPC is not critially required for basic circadian clock.[UniProtKB/Swiss-Prot Function]
Synonyms
KIAA1737
Gene ID
85457
UniProt
Q9C0C6
Accession Number mRNA
NM_033426
Chromosomal Location
14q24.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
42.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CIPC
Species
Human
Protein ID
NP_219494
Overview
Recombinant protein of human KIAA1737 (KIAA1737)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/85457
Uniprot URL
https://www.uniprot.org/uniprot/Q9C0C6
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_033426
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_219494
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