GABPA (NM_002040) Human Recombinant Protein
Product Specifications
Background
This gene encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2010]
Synonyms
E4TF1-60; E4TF1A; NFT2; NRF2; NRF2A; RCH04A07
Gene ID
2551
UniProt
Q06546, A8IE48, Q8IYS3
Accession Number mRNA
NM_002040
Chromosomal Location
21q21.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Transcription Factors
Molecular Weight
51.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
GABPA
Species
Human
Protein ID
NP_002031
Overview
Recombinant protein of human GA binding protein transcription factor, alpha subunit 60kDa (GABPA)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/2551
Uniprot URL
https://www.uniprot.org/uniprot/Q06546
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002040
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002031
Curated Selection
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