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GABPA (NM_002040) Human Recombinant Protein

Product Specifications

Background

This gene encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2010]

Overview

Recombinant protein of human GA binding protein transcription factor, alpha subunit 60kDa (GABPA)

Synonyms

E4TF1-60; E4TF1A; NFT2; NRF2; NRF2A; RCH04A07

Gene ID

2551

UniProt

Q06546, A8IE48, Q8IYS3

Accession Number mRNA

NM_002040

Chromosomal Location

21q21.3

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Transcription Factors

Molecular Weight

51.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

GABPA

Species

Human

Protein ID

NP_002031

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/2551

Uniprot URL

https://www.uniprot.org/uniprot/Q06546

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_002040

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_002031

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