PBP (PEBP1) (NM_002567) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the phosphatidylethanolamine-binding family of proteins and has been shown to modulate multiple signaling pathways, including the MAP kinase (MAPK), NF-kappa B, and glycogen synthase kinase-3 (GSK-3) signaling pathways. The encoded protein can be further processed to form a smaller cleavage product, hippocampal cholinergic neurostimulating peptide (HCNP), which may be involved in neural development. This gene has been implicated in numerous human cancers and may act as a metastasis suppressor gene. Multiple pseudogenes of this gene have been identified in the genome. [provided by RefSeq, Jul 2015]
Synonyms
HCNP; HCNPpp; HEL-210; HEL-S-34; HEL-S-96; PBP; PEBP; PEBP-1; RKIP
Gene ID
5037
UniProt
P30086, D9IAI1
Accession Number mRNA
NM_002567
Chromosomal Location
12q24.23
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
20.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PEBP1
Species
Human
Protein ID
NP_002558
Overview
Recombinant protein of human phosphatidylethanolamine binding protein 1 (PEBP1)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/5037
Uniprot URL
https://www.uniprot.org/uniprot/P30086
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002567
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002558
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