SHC4 (NM_203349) Human Recombinant Protein
Product Specifications
Background
Activates both Ras-dependent and Ras-independent migratory pathways in melanomas. Contributes to the early phases of agrin-induced tyrosine phosphorylation of CHRNB1.[UniProtKB/Swiss-Prot Function]
Overview
Recombinant protein of human SHC (Src homology 2 domain containing) family, member 4 (SHC4)
Synonyms
RaLP; SHCD
Gene ID
399694
UniProt
Q6S5L8
Accession Number mRNA
NM_203349
Chromosomal Location
15q21.1
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Chemokine signaling pathway, Chronic myeloid leukemia, ErbB signaling pathway, Focal adhesion, Glioma, Insulin signaling pathway, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway
Field of Research
Chemokine signaling pathway, Chronic myeloid leukemia, ErbB signaling pathway, Focal adhesion, Glioma, Insulin signaling pathway, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
68.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
SHC4
Species
Human
Protein ID
NP_976224
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/399694
Uniprot URL
https://www.uniprot.org/uniprot/Q6S5L8
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_203349
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_976224
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