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SHC4 (NM_203349) Human Recombinant Protein

Product Specifications

Background

Activates both Ras-dependent and Ras-independent migratory pathways in melanomas. Contributes to the early phases of agrin-induced tyrosine phosphorylation of CHRNB1.[UniProtKB/Swiss-Prot Function]

Overview

Recombinant protein of human SHC (Src homology 2 domain containing) family, member 4 (SHC4)

Synonyms

RaLP; SHCD

Gene ID

399694

UniProt

Q6S5L8

Accession Number mRNA

NM_203349

Chromosomal Location

15q21.1

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Chemokine signaling pathway, Chronic myeloid leukemia, ErbB signaling pathway, Focal adhesion, Glioma, Insulin signaling pathway, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway

Field of Research

Chemokine signaling pathway, Chronic myeloid leukemia, ErbB signaling pathway, Focal adhesion, Glioma, Insulin signaling pathway, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

68.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

SHC4

Species

Human

Protein ID

NP_976224

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/399694

Uniprot URL

https://www.uniprot.org/uniprot/Q6S5L8

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_203349

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_976224

Frequently Asked Questions

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