FBXL2 (NM_012157) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains 12 tandem leucine-rich repeats. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]
Overview
Purified recombinant protein of Homo sapiens F-box and leucine-rich repeat protein 2 (FBXL2)
Synonyms
FBL2; FBL3
Gene ID
25827
UniProt
Q9UKC9
Accession Number mRNA
NM_012157
Chromosomal Location
3p22.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
46.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
FBXL2
Species
Human
Protein ID
NP_036289
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/25827
Uniprot URL
https://www.uniprot.org/uniprot/Q9UKC9
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_012157
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_036289
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog