DENND1C (NM_024898) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene functions as a guanine nucleotide exchange factor for the early endosomal small GTPase RAB35, which regulates endosomal membrane trafficking and is involved in actin polymerization. The encoded protein activates RAB35 by promoting the exchange of RAB35-bound GDP for GTP. This gene may play a role in linking RAB35 activation with the clathrin machinery. [provided by RefSeq, May 2017]
Overview
Recombinant protein of human DENN/MADD domain containing 1C (DENND1C)
Synonyms
FAM31C
Gene ID
79958
UniProt
Q8IV53
Accession Number mRNA
NM_024898
Chromosomal Location
19p13.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
86.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
DENND1C
Species
Human
Protein ID
NP_079174
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/79958
Uniprot URL
https://www.uniprot.org/uniprot/Q8IV53
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_024898
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_079174
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