CYP4F12 (NM_023944) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein likely localizes to the endoplasmic reticulum. When expressed in yeast the enzyme is capable of oxdizing arachidonic acid. It can also catalyze the epoxidation of 22:6n-3 and 22:5n-3 polyunsaturated long-chain fatty acids. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
Overview
Recombinant protein of human cytochrome P450, family 4, subfamily F, polypeptide 12 (CYP4F12)
Synonyms
CYPIVF12; F22329_1
Gene ID
66002
UniProt
Q9HCS2
Accession Number mRNA
NM_023944
Chromosomal Location
19p13.12
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, P450, Transmembrane
Molecular Weight
60.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CYP4F12
Species
Human
Protein ID
NP_076433
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/66002
Uniprot URL
https://www.uniprot.org/uniprot/Q9HCS2
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_023944
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_076433
Frequently Asked Questions
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