RGS3 (NM_134427) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the regulator of G-protein signaling (RGS) family. This protein is a GTPase-activating protein that inhibits G-protein-mediated signal transduction. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms. Long isoforms are largely cytosolic and plasma membrane-associated with a function in Wnt signaling and in the epithelial mesenchymal transition, while shorter N-terminally-truncated isoforms can be nuclear. [provided by RefSeq, Jan 2013]

Overview

Recombinant protein of human regulator of G-protein signaling 3 (RGS3), transcript variant 4

Synonyms

C2PA; RGP3

Gene ID

5998

UniProt

P49796, H7BXY1

Accession Number mRNA

NM_134427

Chromosomal Location

9q32

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Axon guidance

Field of Research

Axon guidance

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

19.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.