ABCG1 (NM_016818) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White) . This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types. Six alternative splice variants have been identified. [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human ATP-binding cassette, sub-family G (WHITE), member 1 (ABCG1), transcript variant 2
Synonyms
ABC8; WHITE1
Gene ID
9619
UniProt
P45844
Accession Number mRNA
NM_016818
Chromosomal Location
21q22.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
ABC transporters
Field of Research
ABC transporters
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transmembrane
Molecular Weight
74 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ABCG1
Species
Human
Protein ID
NP_058198
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/9619
Uniprot URL
https://www.uniprot.org/uniprot/P45844
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_016818
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_058198
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