FKBP11 (NM_016594) Human Recombinant Protein
Product Specifications
Background
FKBP11 belongs to the FKBP family of peptidyl-prolyl cis/trans isomerases, which catalyze the folding of proline-containing polypeptides. The peptidyl-prolyl isomerase activity of FKBP proteins is inhibited by the immunosuppressant compounds FK506 and rapamycin (Rulten et al., 2006 [PubMed 16596453]) .[supplied by OMIM, Mar 2008]
Overview
Recombinant protein of human FK506 binding protein 11, 19 kDa (FKBP11), transcript variant 1
Synonyms
FKBP19
Gene ID
51303
UniProt
Q9NYL4
Accession Number mRNA
NM_016594
Chromosomal Location
12q13.12
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transmembrane
Molecular Weight
19.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
FKBP11
Species
Human
Protein ID
NP_057678
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/51303
Uniprot URL
https://www.uniprot.org/uniprot/Q9NYL4
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_016594
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_057678
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