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DHX30 (NM_014966) Human Recombinant Protein

Product Specifications

Background

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The family member encoded by this gene is a mitochondrial nucleoid protein that associates with mitochondrial DNA. It has also been identified as a component of a transcriptional repressor complex that functions in retinal development, and it is required to optimize the function of the zinc-finger antiviral protein. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2013]

Synonyms

DDX30; NEDMIAL; RETCOR

Gene ID

22907

UniProt

Q7L2E3

Accession Number mRNA

NM_014966

Chromosomal Location

3p21.31

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

129.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

DHX30

Species

Human

Protein ID

NP_055781

Overview

Recombinant protein of human DEAH (Asp-Glu-Ala-His) box polypeptide 30 (DHX30), transcript variant 2

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/22907

Uniprot URL

https://www.uniprot.org/uniprot/Q7L2E3

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_014966

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_055781

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