ROR gamma (RORC) (NM_005060) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known; however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms
IMD42; NR1F3; RORG; RZR-GAMMA; RZRG; TOR
Gene ID
6097
UniProt
P51449, Q6I9R9
Accession Number mRNA
NM_005060
Chromosomal Location
1q21.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transcription Factors
Molecular Weight
58 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
RORC
Species
Human
Protein ID
NP_005051
Overview
Recombinant protein of human RAR-related orphan receptor C (RORC), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/6097
Uniprot URL
https://www.uniprot.org/uniprot/P51449
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_005060
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_005051
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