GRAP2 (NM_004810) Human Recombinant Protein
Selected Variant
PH38859M5
Size: 20 µg
Product Specifications
Background
This gene encodes a member of the GRB2/Sem5/Drk family. This member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related family member, GRB2-related adaptor protein (GRAP), this protein contains an SH2 domain flanked by two SH3 domains. This protein interacts with other proteins, such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2), through its SH3 domains. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
Overview
Recombinant protein of human GRB2-related adaptor protein 2 (GRAP2)
Synonyms
GADS; GRAP-2; GRB2L; GRBLG; GrbX; Grf40; GRID; GRPL; Mona; P38
Gene ID
9402
UniProt
O75791, Q6FI14
Accession Number mRNA
NM_004810
Chromosomal Location
22q13.1
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
T cell receptor signaling pathway
Field of Research
T cell receptor signaling pathway
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
37.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
GRAP2
Species
Human
Protein ID
NP_004801
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/9402
Uniprot URL
https://www.uniprot.org/uniprot/O75791
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_004810
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_004801
Price
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