ARSB (NM_198709) Human Recombinant Protein

Product Specifications

Background

Arylsulfatase B encoded by this gene belongs to the sulfatase family. The arylsulfatase B homodimer hydrolyzes sulfate groups of N-Acetyl-D-galactosamine, chondriotin sulfate, and dermatan sulfate. The protein is targeted to the lysozyme. Mucopolysaccharidosis type VI is an autosomal recessive lysosomal storage disorder resulting from a deficiency of arylsulfatase B. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2016]

Overview

Recombinant protein of human arylsulfatase B (ARSB), transcript variant 2

Synonyms

ASB; G4S; MPS6

Gene ID

411

UniProt

P15848, A8K4A0

Accession Number mRNA

NM_198709

Chromosomal Location

5q14.1

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Glycosaminoglycan degradation, Lysosome, Metabolic pathways

Field of Research

Glycosaminoglycan degradation, Lysosome, Metabolic pathways

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

42.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.