What is the catalog number for PDE1B (NM_000924) Human Recombinant Protein?

The catalog number for PDE1B (NM_000924) Human Recombinant Protein is PH38837M5.

What sizes are available for PDE1B (NM_000924) Human Recombinant Protein?

PDE1B (NM_000924) Human Recombinant Protein is available in the following size(s): 20 µg.

Is PDE1B (NM_000924) Human Recombinant Protein in stock?

PDE1B (NM_000924) Human Recombinant Protein is currently made to order / not held in immediate stock. Contact us for lead time.

PDE1B (NM_000924) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]

Overview

Recombinant protein of human phosphodiesterase 1B, calmodulin-dependent (PDE1B)

Synonyms

HEL-S-79p; PDE1B1; PDES1B

Gene ID

5153

UniProt

Q01064, A0A024RB59

Accession Number mRNA

NM_000924

Chromosomal Location

12q13.2

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Calcium signaling pathway, Progesterone-mediated oocyte maturation, Purine metabolism

Field of Research

Calcium signaling pathway, Progesterone-mediated oocyte maturation, Purine metabolism

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

61.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.