GCAP1 (GUCA1A) (NM_000409) Human Recombinant Protein
Product Specifications
Background
This gene encodes an enzyme that plays a role in the recovery of retinal photoreceptors from photobleaching. This enzyme promotes the activity of retinal guanylyl cyclase-1 (GC1) at low calcium concentrations and inhibits GC1 at high calcium concentrations. Mutations in this gene can cause cone dystrophy 3 and code-rod dystrophy 14. provided by RefSeq, Jul 2020]
Synonyms
C6orf131; COD3; CORD14; GCAP; GCAP1; GUCA; GUCA1
Gene ID
2978
UniProt
P43080
Accession Number mRNA
NM_000409
Chromosomal Location
6p21.1
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Olfactory transduction
Field of Research
Olfactory transduction
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
22.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
GUCA1A
Species
Human
Protein ID
NP_000400
Overview
Recombinant protein of human guanylate cyclase activator 1A (retina) (GUCA1A)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/2978
Uniprot URL
https://www.uniprot.org/uniprot/P43080
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_000409
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_000400
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