GCAP1 (GUCA1A) (NM_000409) Human Recombinant Protein

Product Specifications

Background

This gene encodes an enzyme that plays a role in the recovery of retinal photoreceptors from photobleaching. This enzyme promotes the activity of retinal guanylyl cyclase-1 (GC1) at low calcium concentrations and inhibits GC1 at high calcium concentrations. Mutations in this gene can cause cone dystrophy 3 and code-rod dystrophy 14. provided by RefSeq, Jul 2020]

Overview

Recombinant protein of human guanylate cyclase activator 1A (retina) (GUCA1A)

Synonyms

C6orf131; COD3; CORD14; GCAP; GCAP1; GUCA; GUCA1

Gene ID

2978

UniProt

P43080

Accession Number mRNA

NM_000409

Chromosomal Location

6p21.1

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Olfactory transduction

Field of Research

Olfactory transduction

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

22.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.