CD42a (GP9) (NM_000174) Human Recombinant Protein
Product Specifications
Background
This gene encodes a small membrane glycoprotein found on the surface of human platelets. It forms a 1-to-1 noncovalent complex with glycoprotein Ib, a platelet surface membrane glycoprotein complex that functions as a receptor for von Willebrand factor. The complete receptor complex includes noncovalent association of the alpha and beta subunits with the protein encoded by this gene and platelet glycoprotein V. Defects in this gene are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency. [provided by RefSeq, Oct 2008]
Overview
Recombinant protein of human glycoprotein IX (platelet) (GP9)
Synonyms
CD42a; GPIX
Gene ID
2815
UniProt
P14770
Accession Number mRNA
NM_000174
Chromosomal Location
3q21.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
ECM-receptor interaction, Hematopoietic cell lineage
Field of Research
ECM-receptor interaction, Hematopoietic cell lineage
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transmembrane
Molecular Weight
17.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
GP9
Species
Human
Protein ID
NP_000165
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/2815
Uniprot URL
https://www.uniprot.org/uniprot/P14770
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_000174
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_000165
Frequently Asked Questions
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