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CD42a (GP9) (NM_000174) Human Recombinant Protein

Product Specifications

Background

This gene encodes a small membrane glycoprotein found on the surface of human platelets. It forms a 1-to-1 noncovalent complex with glycoprotein Ib, a platelet surface membrane glycoprotein complex that functions as a receptor for von Willebrand factor. The complete receptor complex includes noncovalent association of the alpha and beta subunits with the protein encoded by this gene and platelet glycoprotein V. Defects in this gene are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency. [provided by RefSeq, Oct 2008]

Overview

Recombinant protein of human glycoprotein IX (platelet) (GP9)

Synonyms

CD42a; GPIX

Gene ID

2815

UniProt

P14770

Accession Number mRNA

NM_000174

Chromosomal Location

3q21.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

ECM-receptor interaction, Hematopoietic cell lineage

Field of Research

ECM-receptor interaction, Hematopoietic cell lineage

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Transmembrane

Molecular Weight

17.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

GP9

Species

Human

Protein ID

NP_000165

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/2815

Uniprot URL

https://www.uniprot.org/uniprot/P14770

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_000174

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_000165

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