Amphiphysin (AMPH) (NM_001635) Human Recombinant Protein
Product Specifications
Background
This gene encodes a protein associated with the cytoplasmic surface of synaptic vesicles. A subset of patients with stiff-man syndrome who were also affected by breast cancer are positive for autoantibodies against this protein. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences have not been determined. A pseudogene of this gene is found on chromosome 11.[provided by RefSeq, Nov 2010]
Overview
Recombinant protein of human amphiphysin (AMPH), transcript variant 1
Synonyms
AMPH1
Gene ID
273
UniProt
P49418
Accession Number mRNA
NM_001635
Chromosomal Location
7p14.1
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Fc gamma R-mediated phagocytosis
Field of Research
Fc gamma R-mediated phagocytosis
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Secreted Protein
Molecular Weight
76.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
AMPH
Species
Human
Protein ID
NP_001626
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/273
Uniprot URL
https://www.uniprot.org/uniprot/P49418
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001635
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001626
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