ALOX15 (NM_001140) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the lipoxygenase family of proteins. The encoded enzyme acts on various polyunsaturated fatty acid substrates to generate various bioactive lipid mediators such as eicosanoids, hepoxilins, lipoxins, and other molecules. The encoded enzyme and its reaction products have been shown to regulate inflammation and immunity. Multiple pseudogenes of this gene have been identified in the human genome. [provided by RefSeq, Aug 2017]
Synonyms
12-LOX; 15-LOX-1; 15LOX-1; LOG15
Gene ID
246
UniProt
P16050
Accession Number mRNA
NM_001140
Chromosomal Location
17p13.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Arachidonic acid metabolism, Linoleic acid metabolism, Metabolic pathways
Field of Research
Arachidonic acid metabolism, Linoleic acid metabolism, Metabolic pathways
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
74.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ALOX15
Species
Human
Protein ID
NP_001131
Overview
Recombinant protein of human arachidonate 15-lipoxygenase (ALOX15)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/246
Uniprot URL
https://www.uniprot.org/uniprot/P16050
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001140
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001131
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