Plzf (ZBTB16) (NM_006006) Human Recombinant Protein
Product Specifications
Background
This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL) . Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human zinc finger and BTB domain containing 16 (ZBTB16), transcript variant 1
Synonyms
PLZF; ZNF145
Gene ID
7704
UniProt
Q05516, A0A024R3C6
Accession Number mRNA
NM_006006
Chromosomal Location
11q23.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Acute myeloid leukemia, Pathways in cancer
Field of Research
Acute myeloid leukemia, Pathways in cancer
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transcription Factors
Molecular Weight
74.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ZBTB16
Species
Human
Protein ID
NP_005997
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/7704
Uniprot URL
https://www.uniprot.org/uniprot/Q05516
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_006006
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_005997
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