RDHE2 (SDR16C5) (NM_138969) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the short-chain alcohol dehydrogenase/reductase superfamily of proteins and is involved in the oxidation of retinol to retinaldehyde. The encoded protein is associated with the endoplasmic reticulum and is predicted to contain three transmembrane helices, suggesting that it is an integral membrane protein. It recognizes all-trans-retinol and all-trans-retinaldehyde as substrates and exhibits a strong preference for NAD (+) /NADH as cofactors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Overview
Recombinant protein of human short chain dehydrogenase/reductase family 16C, member 5 (SDR16C5)
Synonyms
EPHD-2; RDH#2; RDH-E2; RDHE2; retSDR2
Gene ID
195814
UniProt
Q8N3Y7, B3KT84
Accession Number mRNA
NM_138969
Chromosomal Location
8q12.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
33.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
SDR16C5
Species
Human
Protein ID
NP_620419
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/195814
Uniprot URL
https://www.uniprot.org/uniprot/Q8N3Y7
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_138969
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_620419
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