ME1 (NM_002395) Human Recombinant Protein
Product Specifications
Background
This gene encodes a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet. [provided by RefSeq, Jul 2008]
Synonyms
HUMNDME; MES
Gene ID
4199
UniProt
P48163
Accession Number mRNA
NM_002395
Chromosomal Location
6q14.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Metabolic pathways, PPAR signaling pathway, Pyruvate metabolism
Field of Research
Metabolic pathways, PPAR signaling pathway, Pyruvate metabolism
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
64 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ME1
Species
Human
Protein ID
NP_002386
Overview
Recombinant protein of human malic enzyme 1, NADP (+) -dependent, cytosolic (ME1)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/4199
Uniprot URL
https://www.uniprot.org/uniprot/P48163
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002395
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002386
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