Ornithine Decarboxylase (ODC1) (NM_002539) Human Recombinant Protein
Product Specifications
Background
This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Dec 2013]
Overview
Recombinant protein of human ornithine decarboxylase 1 (ODC1)
Synonyms
BABS; NEDBA; NEDBIA; ODC
Gene ID
4953
UniProt
P11926
Accession Number mRNA
NM_002539
Chromosomal Location
2p25.1
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Arginine and proline metabolism, Glutathione metabolism, Metabolic pathways
Field of Research
Arginine and proline metabolism, Glutathione metabolism, Metabolic pathways
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Activity
2725778728346093
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
51 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ODC1
Species
Human
Protein ID
NP_002530
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/4953
Uniprot URL
https://www.uniprot.org/uniprot/P11926
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002539
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002530
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