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HPD (NM_002150) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is an enzyme in the catabolic pathway of tyrosine. The encoded protein catalyzes the conversion of 4-hydroxyphenylpyruvate to homogentisate. Defects in this gene are a cause of tyrosinemia type 3 (TYRO3) and hawkinsinuria (HAWK) . Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]

Overview

Recombinant protein of human 4-hydroxyphenylpyruvate dioxygenase (HPD)

Synonyms

4-HPPD; 4HPPD; GLOD3; HPPDASE; PPD

Gene ID

3242

UniProt

P32754

Accession Number mRNA

NM_002150

Chromosomal Location

12q24.31

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Metabolic pathways, Phenylalanine metabolism, Tyrosine metabolism, Ubiquinone and other terpenoid-quinone biosynthesis

Field of Research

Metabolic pathways, Phenylalanine metabolism, Tyrosine metabolism, Ubiquinone and other terpenoid-quinone biosynthesis

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

44.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

HPD

Species

Human

Protein ID

NP_002141

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/3242

Uniprot URL

https://www.uniprot.org/uniprot/P32754

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_002150

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_002141

Frequently Asked Questions

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