PPP2R5B (NM_006244) Human Recombinant Protein
Product Specifications
Background
The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a beta isoform of the regulatory subunit B56 subfamily. [provided by RefSeq, Jul 2008]
Synonyms
B56B; B56beta; PR61B
Gene ID
5526
UniProt
Q15173, A0A024R593
Accession Number mRNA
NM_006244
Chromosomal Location
11q13.1
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Oocyte meiosis, Wnt signaling pathway
Field of Research
Oocyte meiosis, Wnt signaling pathway
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Phosphatase
Molecular Weight
57.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PPP2R5B
Species
Human
Protein ID
NP_006235
Overview
Recombinant protein of human protein phosphatase 2, regulatory subunit B', beta isoform (PPP2R5B)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/5526
Uniprot URL
https://www.uniprot.org/uniprot/Q15173
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_006244
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_006235
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