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PPP2R5B (NM_006244) Human Recombinant Protein

Product Specifications

Background

The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a beta isoform of the regulatory subunit B56 subfamily. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human protein phosphatase 2, regulatory subunit B', beta isoform (PPP2R5B)

Synonyms

B56B; B56beta; PR61B

Gene ID

5526

UniProt

Q15173, A0A024R593

Accession Number mRNA

NM_006244

Chromosomal Location

11q13.1

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Oocyte meiosis, Wnt signaling pathway

Field of Research

Oocyte meiosis, Wnt signaling pathway

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Phosphatase

Molecular Weight

57.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

PPP2R5B

Species

Human

Protein ID

NP_006235

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/5526

Uniprot URL

https://www.uniprot.org/uniprot/Q15173

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_006244

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_006235

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