DUSP28 (NM_001033575) Human Recombinant Protein
Product Specifications
Background
Has phosphatase activity with the synthetic substrate 6,8-difluoro-4-methylumbelliferyl phosphate (in vitro) (PubMed:24531476, PubMed:29121083) . Has almost no detectable activity with phosphotyrosine, even less activity with phosphothreonine and displays complete lack of activity with phosphoserine (PubMed:29121083) . The poor activity with phosphotyrosine may be due to steric hindrance by bulky amino acid sidechains that obstruct access to the active site (PubMed:29121083) .[UniProtKB/Swiss-Prot Function]
Overview
Recombinant protein of human dual specificity phosphatase 28 (DUSP28)
Synonyms
DUSP26; VHP
Gene ID
285193
UniProt
Q4G0W2
Accession Number mRNA
NM_001033575
Chromosomal Location
2q37.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
18.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
DUSP28
Species
Human
Protein ID
NP_001028747
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/285193
Uniprot URL
https://www.uniprot.org/uniprot/Q4G0W2
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001033575
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001028747
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