PRAM1 (NM_032152) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is similar to FYN binding protein (FYB/SLAP-130), an adaptor protein involved in T cell receptor mediated signaling. This gene is expressed and regulated during normal myelopoiesis. The expression of this gene is induced by retinoic acid and is inhibited by the expression of PML-RARalpha, a fusion protein of promyelocytic leukemia (PML) and the retinoic acid receptor-alpha (RARalpha) . [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human PML-RARA regulated adaptor molecule 1 (PRAM1)
Synonyms
PML-RAR; PRAM-1
Gene ID
84106
UniProt
Q96QH2
Accession Number mRNA
NM_032152
Chromosomal Location
19p13.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
73.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PRAM1
Species
Human
Protein ID
NP_115528
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/84106
Uniprot URL
https://www.uniprot.org/uniprot/Q96QH2
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_032152
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_115528
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