NUP50 (NM_153645) Human Recombinant Protein
Product Specifications
Background
The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins that functions as a soluble cofactor in importin-alpha:beta-mediated nuclear protein import. Pseudogenes of this gene are found on chromosomes 5, 6, and 14. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms
NPAP60; NPAP60L
Gene ID
10762
UniProt
Q9UKX7
Accession Number mRNA
NM_153645
Chromosomal Location
22q13.31
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Stem cell - Pluripotency
Molecular Weight
46.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
NUP50
Species
Human
Protein ID
NP_705931
Overview
Recombinant protein of human nucleoporin 50kDa (NUP50), transcript variant 3
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/10762
Uniprot URL
https://www.uniprot.org/uniprot/Q9UKX7
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_153645
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_705931
Curated Selection
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