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NUP50 (NM_153645) Human Recombinant Protein

Product Specifications

Background

The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins that functions as a soluble cofactor in importin-alpha:beta-mediated nuclear protein import. Pseudogenes of this gene are found on chromosomes 5, 6, and 14. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human nucleoporin 50kDa (NUP50), transcript variant 3

Synonyms

NPAP60; NPAP60L

Gene ID

10762

UniProt

Q9UKX7

Accession Number mRNA

NM_153645

Chromosomal Location

22q13.31

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Stem cell - Pluripotency

Molecular Weight

46.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

NUP50

Species

Human

Protein ID

NP_705931

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/10762

Uniprot URL

https://www.uniprot.org/uniprot/Q9UKX7

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_153645

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_705931

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