C7orf16 (PPP1R17) (NM_006658) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is found primarily in cerebellar Purkinje cells, where it functions as a protein phosphatase inhibitor. The encoded protein is a substrate for cGMP-dependent protein kinase. An allele of this gene was discovered that increases susceptibility to hypercholesterolemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
Synonyms
C7orf16; GSBS
Gene ID
10842
UniProt
O96001, A0A090N8N7
Accession Number mRNA
NM_006658
Chromosomal Location
7p14.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Long-term depression
Field of Research
Long-term depression
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
17.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PPP1R17
Species
Human
Protein ID
NP_006649
Overview
Recombinant protein of human chromosome 7 open reading frame 16 (C7orf16), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/10842
Uniprot URL
https://www.uniprot.org/uniprot/O96001
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_006658
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_006649
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