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C7orf16 (PPP1R17) (NM_006658) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is found primarily in cerebellar Purkinje cells, where it functions as a protein phosphatase inhibitor. The encoded protein is a substrate for cGMP-dependent protein kinase. An allele of this gene was discovered that increases susceptibility to hypercholesterolemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]

Overview

Recombinant protein of human chromosome 7 open reading frame 16 (C7orf16), transcript variant 1

Synonyms

C7orf16; GSBS

Gene ID

10842

UniProt

O96001, A0A090N8N7

Accession Number mRNA

NM_006658

Chromosomal Location

7p14.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Long-term depression

Field of Research

Long-term depression

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

17.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

PPP1R17

Species

Human

Protein ID

NP_006649

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/10842

Uniprot URL

https://www.uniprot.org/uniprot/O96001

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_006658

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_006649

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