UBE2L6 (NM_198183) Human Recombinant Protein
Product Specifications
Background
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s) . This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is highly similar in primary structure to the enzyme encoded by the UBE2L3 gene. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2011]
Synonyms
RIG-B; UBCH8
Gene ID
9246
UniProt
O14933, Q8N5D8
Accession Number mRNA
NM_198183
Chromosomal Location
11q12.1
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Parkinson's disease, Ubiquitin mediated proteolysis
Field of Research
Parkinson's disease, Ubiquitin mediated proteolysis
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
9.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
UBE2L6
Species
Human
Protein ID
NP_937826
Overview
Recombinant protein of human ubiquitin-conjugating enzyme E2L 6 (UBE2L6), transcript variant 2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/9246
Uniprot URL
https://www.uniprot.org/uniprot/O14933
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_198183
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_937826
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