SYVN1 (NM_032431) Human Recombinant Protein
Product Specifications
Background
This gene encodes a protein involved in endoplasmic reticulum (ER) -associated degradation. The encoded protein removes unfolded proteins, accumulated during ER stress, by retrograde transport to the cytosol from the ER. This protein also uses the ubiquitin-proteasome system for additional degradation of unfolded proteins. Sequence analysis identified two transcript variants that encode different isoforms. [provided by RefSeq, May 2011]
Synonyms
DER3; HRD1
Gene ID
84447
UniProt
Q86TM6
Accession Number mRNA
NM_032431
Chromosomal Location
11q13.1
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Ubiquitin mediated proteolysis
Field of Research
Ubiquitin mediated proteolysis
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transmembrane
Molecular Weight
67.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
SYVN1
Species
Human
Protein ID
NP_115807
Overview
Recombinant protein of human synovial apoptosis inhibitor 1, synoviolin (SYVN1), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/84447
Uniprot URL
https://www.uniprot.org/uniprot/Q86TM6
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_032431
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_115807
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