UPP2 (NM_173355) Human Recombinant Protein
Product Specifications
Background
Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows substrate specificity and accept uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2 (') -deoxyuridine as substrates.[UniProtKB/Swiss-Prot Function]
Synonyms
UDRPASE2; UP2; UPASE2
Gene ID
151531
UniProt
O95045, A0A0S2Z634
Accession Number mRNA
NM_173355
Chromosomal Location
2q24.1
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Drug metabolism - other enzymes, Metabolic pathways, Pyrimidine metabolism
Field of Research
Drug metabolism - other enzymes, Metabolic pathways, Pyrimidine metabolism
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
35.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
UPP2
Species
Human
Protein ID
NP_775491
Overview
Recombinant protein of human uridine phosphorylase 2 (UPP2), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/151531
Uniprot URL
https://www.uniprot.org/uniprot/O95045
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_173355
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_775491
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
