DARS2 (NM_018122) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. It is a mitochondrial enzyme that specifically aminoacylates aspartyl-tRNA. Mutations in this gene are associated with leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL) . [provided by RefSeq, Nov 2009]
Synonyms
ASPRS; LBSL; MT-ASPRS; mtAspRS
Gene ID
55157
UniProt
Q6PI48, Q9H9J7
Accession Number mRNA
NM_018122
Chromosomal Location
1q25.1
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Aminoacyl-tRNA biosynthesis
Field of Research
Aminoacyl-tRNA biosynthesis
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
73.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
DARS2
Species
Human
Protein ID
NP_060592
Overview
Recombinant protein of human aspartyl-tRNA synthetase 2, mitochondrial (DARS2), nuclear gene encoding mitochondrial protein
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/55157
Uniprot URL
https://www.uniprot.org/uniprot/Q6PI48
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_018122
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_060592
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