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EXTL2 (NM_001439) Human Recombinant Protein

Product Specifications

Background

Glycosyltransferase required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N-acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains.[UniProtKB/Swiss-Prot Function]

Overview

Recombinant protein of human exostoses (multiple) -like 2 (EXTL2), transcript variant 1

Synonyms

EXTR2

Gene ID

2135

UniProt

Q9UBQ6

Accession Number mRNA

NM_001439

Chromosomal Location

1p21.2

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Heparan sulfate biosynthesis

Field of Research

Heparan sulfate biosynthesis

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Transmembrane

Molecular Weight

37.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

EXTL2

Species

Human

Protein ID

NP_001430

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/2135

Uniprot URL

https://www.uniprot.org/uniprot/Q9UBQ6

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001439

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001430

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