EXTL2 (NM_001439) Human Recombinant Protein
Product Specifications
Background
Glycosyltransferase required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N-acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains.[UniProtKB/Swiss-Prot Function]
Overview
Recombinant protein of human exostoses (multiple) -like 2 (EXTL2), transcript variant 1
Synonyms
EXTR2
Gene ID
2135
UniProt
Q9UBQ6
Accession Number mRNA
NM_001439
Chromosomal Location
1p21.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Heparan sulfate biosynthesis
Field of Research
Heparan sulfate biosynthesis
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Transmembrane
Molecular Weight
37.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
EXTL2
Species
Human
Protein ID
NP_001430
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/2135
Uniprot URL
https://www.uniprot.org/uniprot/Q9UBQ6
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001439
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001430
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