Peroxiredoxin 2 (PRDX2) (NM_005809) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8 (+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13. [provided by RefSeq, Mar 2013]
Synonyms
HEL-S-2a; NKEF-B; NKEFB; PRP; PRX2; PRXII; PTX1; TDPX1; TPX1; TSA
Gene ID
7001
UniProt
P32119, V9HW12
Accession Number mRNA
NM_005809
Chromosomal Location
19p13.13
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
21.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PRDX2
Species
Human
Protein ID
NP_005800
Overview
Recombinant protein of human peroxiredoxin 2 (PRDX2), nuclear gene encoding mitochondrial protein, transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/7001
Uniprot URL
https://www.uniprot.org/uniprot/P32119
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_005809
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_005800
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items