MX1 (NM_002462) Human Recombinant Protein
Product Specifications
Background
This gene encodes a guanosine triphosphate (GTP) -metabolizing protein that participates in the cellular antiviral response. The encoded protein is induced by type I and type II interferons and antagonizes the replication process of several different RNA and DNA viruses. There is a related gene located adjacent to this gene on chromosome 21, and there are multiple pseudogenes located in a cluster on chromosome 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Synonyms
IFI-78K; IFI78; lncMX1-215; MX; MxA
Gene ID
4599
UniProt
P20591
Accession Number mRNA
NM_002462
Chromosomal Location
21q22.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
75.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
MX1
Species
Human
Protein ID
NP_002453
Overview
Recombinant protein of human myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) (MX1), transcript variant 2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/4599
Uniprot URL
https://www.uniprot.org/uniprot/P20591
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002462
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002453
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