KCNIP4 (NM_001035004) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. This protein member also interacts with presenilin. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Synonyms
CALP; KCHIP4
Gene ID
80333
UniProt
Q6PIL6, A8K4N3
Accession Number mRNA
NM_001035004
Chromosomal Location
4p15.31-p15.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Ion Channels: Other
Molecular Weight
21.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
KCNIP4
Species
Human
Protein ID
NP_001030176
Overview
Recombinant protein of human Kv channel interacting protein 4 (KCNIP4), transcript variant 6
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/80333
Uniprot URL
https://www.uniprot.org/uniprot/Q6PIL6
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001035004
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001030176
Curated Selection
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