RUFY1 (NM_001040451) Human Recombinant Protein
Product Specifications
Background
This gene encodes a protein that contains a RUN domain and a FYVE-type zinc finger domain. The encoded protein binds to phosphatidylinositol-3-phosphate (PI3P) and plays a role in early endosomal trafficking, tethering and fusion through interactions with small GTPases including Rab4, Rab5 and Rab14. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Overview
Recombinant protein of human RUN and FYVE domain containing 1 (RUFY1), transcript variant 2
Synonyms
RABIP4; ZFYVE12
Gene ID
80230
UniProt
Q96T51, A8K7B1
Accession Number mRNA
NM_001040451
Chromosomal Location
5q35.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Endocytosis
Field of Research
Endocytosis
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
68.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
RUFY1
Species
Human
Protein ID
NP_001035541
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/80230
Uniprot URL
https://www.uniprot.org/uniprot/Q96T51
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001040451
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001035541
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