RUFY1 (NM_001040451) Human Recombinant Protein

Product Specifications

Background

This gene encodes a protein that contains a RUN domain and a FYVE-type zinc finger domain. The encoded protein binds to phosphatidylinositol-3-phosphate (PI3P) and plays a role in early endosomal trafficking, tethering and fusion through interactions with small GTPases including Rab4, Rab5 and Rab14. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

Overview

Recombinant protein of human RUN and FYVE domain containing 1 (RUFY1), transcript variant 2

Synonyms

RABIP4; ZFYVE12

Gene ID

80230

UniProt

Q96T51, A8K7B1

Accession Number mRNA

NM_001040451

Chromosomal Location

5q35.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Endocytosis

Field of Research

Endocytosis

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

68.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.