FNDC4 (NM_022823) Human Recombinant Protein
Product Specifications
Background
Acts as an anti-inflammatory factor in the intestine and colon. Binds to and acts on macrophages to downregulate pro-inflammatory gene expression. Affects key macrophage functions, including phagocytosis, by downregulating many key pathways for macrophage activation, partly via by STAT3 activation and signaling. May be required to dampen the immunological response in colitis.[UniProtKB/Swiss-Prot Function]
Synonyms
FRCP1
Gene ID
64838
UniProt
Q9H6D8
Accession Number mRNA
NM_022823
Chromosomal Location
2p23.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Transmembrane
Molecular Weight
25 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
FNDC4
Species
Human
Protein ID
NP_073734
Overview
Recombinant protein of human fibronectin type III domain containing 4 (FNDC4)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/64838
Uniprot URL
https://www.uniprot.org/uniprot/Q9H6D8
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_022823
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_073734
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items