EEF2K (NM_013302) Human Recombinant Protein
Product Specifications
Background
This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment. [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human eukaryotic elongation factor-2 kinase (EEF2K)
Synonyms
CaMKIII; eEF-2K; HSU93850
Gene ID
29904
UniProt
O00418
Accession Number mRNA
NM_013302
Chromosomal Location
16p12.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Protein Kinase
Molecular Weight
82 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
EEF2K
Species
Human
Protein ID
NP_037434
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/29904
Uniprot URL
https://www.uniprot.org/uniprot/O00418
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_013302
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_037434
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