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SAPS2 (PPP6R2) (NM_014678) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a regulatory protein for the protein phosphatase-6 catalytic subunit. Together, these proteins act as a significant T-loop phosphatase for Aurora A, an essential mitotic kinase. Loss of function of either the regulatory or catalytic subunit of protein phosphatase-6 interferes with spindle formation and chromosome alignment. [provided by RefSeq, May 2017]

Synonyms

KIAA0685; PP6R2; SAP190; SAPS2

Gene ID

9701

UniProt

O75170

Accession Number mRNA

NM_014678

Chromosomal Location

22q13.33

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

101.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

PPP6R2

Species

Human

Protein ID

NP_055493

Overview

Recombinant protein of human SAPS domain family, member 2 (SAPS2)

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/9701

Uniprot URL

https://www.uniprot.org/uniprot/O75170

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_014678

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_055493

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