DHDH (NM_014475) Human Recombinant Protein
Product Specifications
Background
This gene encodes an enzyme that belongs to the family of dihydrodiol dehydrogenases, which exist in multiple forms in mammalian tissues and are involved in the metabolism of xenobiotics and sugars. These enzymes catalyze the NADP1-linked oxidation of transdihydrodiols of aromatic hydrocarbons to corresponding catechols. This enzyme is a dimeric dihydrodiol dehydrogenase, and it differs from monomeric dihydrodiol dehydrogenases in its high substrate specificity for trans-dihydrodiols of aromatic hydrocarbons in the oxidative direction. [provided by RefSeq, Jul 2008]
Synonyms
2DD; HUM2DD
Gene ID
27294
UniProt
Q9UQ10
Accession Number mRNA
NM_014475
Chromosomal Location
19q13.33
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Metabolism of xenobiotics by cytochrome P450
Field of Research
Metabolism of xenobiotics by cytochrome P450
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
36.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
DHDH
Species
Human
Protein ID
NP_055290
Overview
Recombinant protein of human dihydrodiol dehydrogenase (dimeric) (DHDH)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/27294
Uniprot URL
https://www.uniprot.org/uniprot/Q9UQ10
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_014475
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_055290
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