DHDH (NM_014475) Human Recombinant Protein

Product Specifications

Background

This gene encodes an enzyme that belongs to the family of dihydrodiol dehydrogenases, which exist in multiple forms in mammalian tissues and are involved in the metabolism of xenobiotics and sugars. These enzymes catalyze the NADP1-linked oxidation of transdihydrodiols of aromatic hydrocarbons to corresponding catechols. This enzyme is a dimeric dihydrodiol dehydrogenase, and it differs from monomeric dihydrodiol dehydrogenases in its high substrate specificity for trans-dihydrodiols of aromatic hydrocarbons in the oxidative direction. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human dihydrodiol dehydrogenase (dimeric) (DHDH)

Synonyms

2DD; HUM2DD

Gene ID

27294

UniProt

Q9UQ10

Accession Number mRNA

NM_014475

Chromosomal Location

19q13.33

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Metabolism of xenobiotics by cytochrome P450

Field of Research

Metabolism of xenobiotics by cytochrome P450

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

36.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.