RACGAP1 (NM_013277) Human Recombinant Protein
Selected Variant
PH38452M5
Size: 20 µg
Product Specifications
Background
This gene encodes a GTPase-activating protein (GAP) that is a compoment of the centralspindlin complex. This protein binds activated forms of Rho GTPases and stimulates GTP hydrolysis, which results in negative regulation of Rho-mediated signals. This protein plays a regulatory role in cytokinesis, cell growth, and differentiation. Alternatively spliced transcript variants have been found for this gene. There is a pseudogene for this gene on chromosome 12. [provided by RefSeq, Feb 2016]
Overview
Recombinant protein of human Rac GTPase activating protein 1 (RACGAP1), transcript variant 1
Synonyms
CYK4; HsCYK-4; ID-GAP; MgcRacGAP
Gene ID
29127
UniProt
Q9H0H5, A0A024R136
Accession Number mRNA
NM_013277
Chromosomal Location
12q13.12
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
70.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
RACGAP1
Species
Human
Protein ID
NP_037409
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/29127
Uniprot URL
https://www.uniprot.org/uniprot/Q9H0H5
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_013277
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_037409
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