PNK (PNKP) (NM_007254) Human Recombinant Protein
Product Specifications
Background
This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay.[provided by RefSeq, Sep 2010]
Synonyms
AOA4; CMT2B2; EIEE10; MCSZ; PNK
Gene ID
11284
UniProt
Q96T60
Accession Number mRNA
NM_007254
Chromosomal Location
19q13.33
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Phosphatase
Molecular Weight
56.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PNKP
Species
Human
Protein ID
NP_009185
Overview
Recombinant protein of human polynucleotide kinase 3'-phosphatase (PNKP)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/11284
Uniprot URL
https://www.uniprot.org/uniprot/Q96T60
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_007254
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_009185
Curated Selection
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